Common drugs over-temperature sales or produce side effects

Experts say long-term over-temperature storage affects efficacy

"The failure to store medicines as required has certain impact on the efficacy of drugs." Yesterday, Pang Chengsen, a pharmacist of the Department of Pharmacy at Xi'an Jiaotong University Affiliated Hospital, said.

According to a person in charge of Xi'an Food and Drug Administration, according to the definition of some terminology for the storage and storage of pharmaceuticals in the Chinese Pharmacopoeia: “The cool place means no more than 20°C; the cool place means no more than 20 light sources. °C; Cold refers to 2~10°C; Normal refers to 10~30°C." The “Pharmaceutical Business Quality Management Regulations” formally implemented on June 1 this year also clearly stipulates: “If the temperature is required to be stored according to the packaging labeling temperature, if no specific temperature is indicated on the packaging, the storage requirements specified in the “Pharmacopoeia” shall be followed. store". However, in practice, many pharmacies, clinics and even hospitals did not meet the requirements.

“If the actual storage temperature is not significantly different from the labeled temperature of the drug, the impact on the drug is relatively small. If it is stored in a severely over-temperature environment for a long time, it may cause the chemical structure of the drug to change, the concentration of the active ingredient to decrease, and affect the efficacy of the drug. , to shorten the effective period of drugs." Pang Chengsen said, and serious will have degeneration side effects.

Teach you a trick "Shadow preservation" can be refrigerated in the refrigerator

Yesterday, the reporter randomly interviewed 20 citizens. Most of them said they never looked at the storage conditions of drugs. They took them home and placed them in a small medicine chest.

"The state has stringent storage requirements for vaccines and other biological agents and antibiotics, and many daily drug stores, pharmacies and citizens should also be stored as required." Yesterday, a person in charge of Xi'an Food and Drug Administration said that summer indoor The temperature is often above 20°C. At this time, the medicine can be stored in the refrigerator freezer.

The person in charge said that the drugs may change after they expire, but it is very difficult for the public to make judgments. It is very likely that the expiration date will not be recognized. If they are ineffective after taking the drug, they should stop taking them immediately. Antibiotic drugs should be directed by doctors. Taken under, some drugs will be harmful after the expiration of the drug, vitamins, injections, nitroglycerin and other drugs, ultraviolet rays in the sun will accelerate its deterioration, efficacy will also be reduced. In the strong sunshine season, be sure to avoid light and heat.

Pang Chengsen reminded that many families have family medicine kits. It is best to clean them once every six months, and expired medicines are firmly lost.

Know which drugs need to be refrigerated in the summer?

So, what medicines need to be refrigerated? Yesterday, a person in charge of Xi'an Food and Drug Administration said that the public can judge according to the drug's instructions. All drugs should be stored according to the storage conditions marked in the manual.

Sugar-coated tablets, capsules, capsules, powders, granules added with sucrose, ophthalmic preparations, suppositories for the anus, certain suppositories for the treatment of gynecological inflammation, etc., need to be stored in the refrigerator in the summer. Special attention should be paid to the fact that some medicines are particularly sensitive to heat. For example, some stomach medicine enzymes and pepsin need to be kept in a refrigerated state; tinctures usually contain volatile solvents, such as alcohol, and should be tightened after use. Placed in a refrigerator to refrigerate; suppositories and some capsules or capsules will soften, crack, leak oil when the temperature is too high, summer can be placed in the refrigerator; topical drugs, such as eye drops, nose drops, ear drops Liquids, lotions, mouthwashes, etc., are also best kept in refrigerators during the summer to prevent deterioration.

In addition, insulin, biological products, and some diarrhea and topical drugs are also best to be refrigerated during the summer to obtain a longer shelf life.