In the production of pharmaceutical tablet presses, Zui is the key core equipment, affecting most of the quality indicators and economic indicators (qualification rate, etc.). At present, the domestic tablet press models mainly include two types of single punching machine and multi-punch rotary tablet press.
The multi-punch rotary tablet press is a tablet press widely used in production. The automatic high-speed rotary PLC tablet press detects the punch pressure through the pressure sensor, and is monitored and analyzed by the central control unit CPU. The filling depth of the tablet press is adjusted according to the predetermined control model to realize the automatic production of the tablet press. control. At the same time, it monitors the damage of the tablet press and the supply of the powder, which plays a safety protection role, greatly improves the pass rate of the tablets, reduces the production cost, and realizes one-man multi-machine management. The system is simple in operation, convenient in maintenance, stable and reliable in operation, high in control precision, and has high technical advantages.
The single punching machine mainly drives the up and down punching by the rotation of the rotating wheel, and presses the particles filled into the die hole by the powder adding device into a piece. The main drawback is that the impact noise is large when the tablet is pressed (produced by the one-way pressurization of the upper punch), and the output is small (about 100 sheets/min), which is only suitable for production in small batches and trial production in the laboratory.
1. Basic composition The tablet press mainly consists of forced feeding system, stamping combination, filming system, vacuum system and programmable controller (PLC) control box. Its composition and function are as follows:
Forced feeding system: consists of feeding motor, feeding worm gear reducer, universal joint, coupling, forced feeder, bucket, connecting pipe, feeding platform and leveling leg mechanism to fill the material into the die hole.
Stamping combination: consists of punching plate combination, upper and lower punch, middle die, upper and lower pre-pressing wheel, upper and lower main pressing wheel, filling device, upper rail plate and pull-down cam guide to complete the whole pressing process.
The filming system: including the filming system and the dispensing mechanism, the elimination of the defective film and the release of the qualified film.
Vacuum system: The dust of the punching plate and the upper and lower punches is removed by a special vacuum cleaner.
The settings of the equipment operation program and the control contents of the man-machine interface are all displayed on the screen, including the frequency conversion setting of the machine speed, the adjustment of the oil pressure, the control of the feeder feeding, and the counting of the output.
2. Workflow and Features 2.1 Workflow The workflow of this type of tablet press includes processes such as overfilling, quantification, pre-pressing, main-press molding, and filming. The upper and lower punches are driven by the punching plate and move up and down along the upper and lower rails respectively. When the punch runs to the filling section, the upper punching upward movement bypasses the feeder, and the lower punch moves downward through the pull-down cam, and the lower punch The surface forms a cavity with the middle die hole, and the particles are filled into the cavity through the feeder, and an excessive filling is formed when the lower punch passes through the low point of the pull-down cam zui. The punching plate continues to move, and the undershoot gradually moves upward through the filling cam, and the excess particles in the cavity are pushed out of the die hole to enter the quantitative section. In the quantitative section, excess particles of the upper surface of the middle mold are scraped off by a quantitative scraping. The die continues to rotate, the lower punch protects the cam to pull down the lower punch, and the upper punch moves downward under the action of the pull-down cam. When the die hole moves out of the cover, the upper punch enters the middle die. When the punch passes the pre-pressing wheel, the pre-pressing is completed; then the main pressing wheel is continued to complete the tablet pressing; after the Zui, the upper rail is moved up and the cam is raised, the upper punch is moved up, the lower punch is pushed up, and the pressing is performed. A good tablet is introduced and enters the filming device to complete the entire tableting process.
2.2 The main features of the use of mechatronics servo control system. Servo motor is the power source, the output torque and speed accuracy are high, the spindle speed is up to 100r/min, and the Zui high-voltage piece can reach 168KT/H. With the size and shape of the die, it can be pressed out of the large diameter of 13mm. Sheet, zui large-length 16mm shaped piece, average piece weight control accuracy ± 1%, individual piece weight difference:
With various interlock protection and alarm functions: with upper and lower over-tight protection; with main pressure, pre-pressure hydraulic support, hydraulic pressure adjustable and automatic pressure-holding function; with automatic lubrication system, lubrication flow in time interval Adjusted, with a lubricant shortage alarm device; has the function of automatically controlling the weight of the tablet within the error range and rejecting the unqualified product; with overload protection, emergency stop, automatic shutdown alarm function.
The multi-punch rotary tablet press is a tablet press widely used in production. The automatic high-speed rotary PLC tablet press detects the punch pressure through the pressure sensor, and is monitored and analyzed by the central control unit CPU. The filling depth of the tablet press is adjusted according to the predetermined control model to realize the automatic production of the tablet press. control. At the same time, it monitors the damage of the tablet press and the supply of the powder, which plays a safety protection role, greatly improves the pass rate of the tablets, reduces the production cost, and realizes one-man multi-machine management. The system is simple in operation, convenient in maintenance, stable and reliable in operation, high in control precision, and has high technical advantages.
The single punching machine mainly drives the up and down punching by the rotation of the rotating wheel, and presses the particles filled into the die hole by the powder adding device into a piece. The main drawback is that the impact noise is large when the tablet is pressed (produced by the one-way pressurization of the upper punch), and the output is small (about 100 sheets/min), which is only suitable for production in small batches and trial production in the laboratory.
1. Basic composition The tablet press mainly consists of forced feeding system, stamping combination, filming system, vacuum system and programmable controller (PLC) control box. Its composition and function are as follows:
Forced feeding system: consists of feeding motor, feeding worm gear reducer, universal joint, coupling, forced feeder, bucket, connecting pipe, feeding platform and leveling leg mechanism to fill the material into the die hole.
Stamping combination: consists of punching plate combination, upper and lower punch, middle die, upper and lower pre-pressing wheel, upper and lower main pressing wheel, filling device, upper rail plate and pull-down cam guide to complete the whole pressing process.
The filming system: including the filming system and the dispensing mechanism, the elimination of the defective film and the release of the qualified film.
Vacuum system: The dust of the punching plate and the upper and lower punches is removed by a special vacuum cleaner.
The settings of the equipment operation program and the control contents of the man-machine interface are all displayed on the screen, including the frequency conversion setting of the machine speed, the adjustment of the oil pressure, the control of the feeder feeding, and the counting of the output.
2. Workflow and Features 2.1 Workflow The workflow of this type of tablet press includes processes such as overfilling, quantification, pre-pressing, main-press molding, and filming. The upper and lower punches are driven by the punching plate and move up and down along the upper and lower rails respectively. When the punch runs to the filling section, the upper punching upward movement bypasses the feeder, and the lower punch moves downward through the pull-down cam, and the lower punch The surface forms a cavity with the middle die hole, and the particles are filled into the cavity through the feeder, and an excessive filling is formed when the lower punch passes through the low point of the pull-down cam zui. The punching plate continues to move, and the undershoot gradually moves upward through the filling cam, and the excess particles in the cavity are pushed out of the die hole to enter the quantitative section. In the quantitative section, excess particles of the upper surface of the middle mold are scraped off by a quantitative scraping. The die continues to rotate, the lower punch protects the cam to pull down the lower punch, and the upper punch moves downward under the action of the pull-down cam. When the die hole moves out of the cover, the upper punch enters the middle die. When the punch passes the pre-pressing wheel, the pre-pressing is completed; then the main pressing wheel is continued to complete the tablet pressing; after the Zui, the upper rail is moved up and the cam is raised, the upper punch is moved up, the lower punch is pushed up, and the pressing is performed. A good tablet is introduced and enters the filming device to complete the entire tableting process.
2.2 The main features of the use of mechatronics servo control system. Servo motor is the power source, the output torque and speed accuracy are high, the spindle speed is up to 100r/min, and the Zui high-voltage piece can reach 168KT/H. With the size and shape of the die, it can be pressed out of the large diameter of 13mm. Sheet, zui large-length 16mm shaped piece, average piece weight control accuracy ± 1%, individual piece weight difference:
With various interlock protection and alarm functions: with upper and lower over-tight protection; with main pressure, pre-pressure hydraulic support, hydraulic pressure adjustable and automatic pressure-holding function; with automatic lubrication system, lubrication flow in time interval Adjusted, with a lubricant shortage alarm device; has the function of automatically controlling the weight of the tablet within the error range and rejecting the unqualified product; with overload protection, emergency stop, automatic shutdown alarm function.
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