Improve the efficiency of tank checking tank to ensure efficient and error-free production

[China Pharmaceutical Network Technical Principles] After decades of development, China's fermentation industry has penetrated into various aspects such as medicine, agriculture, environmental protection, energy and materials from the original antibiotics and food. The structure of the fermentation industry has also gradually shifted to a new generation of fermentation products that can improve people's quality of life. At present, China's fermentation industry is developing rapidly, and the annual output value is also rising year by year.

The continuous development of the fermentation industry stimulates the fermenter to move toward a more efficient and safer situation. The fermenter is a device used for microbial fermentation in the industry. It is suitable for the production of various products. It has been widely used in food, medicine, environmental science and other fields, and contributes to the modern fermentation industry.

(fermentation tank produced by Jiangsu Fluude Fluid Equipment Co., Ltd.)

The fermenter is powerful and mainly used in three fields.

Fermentation tank is a kind of equipment for mechanical agitation and fermentation of materials. It usually adopts the method of internal circulation, disperses and breaks bubbles with a stirring paddle, and has high dissolved oxygen rate and good mixing effect. Fermenters are distinguished from other industrial equipment. In general, fermenters are very demanding for pure culture, even to a very demanding level. Therefore, the rigor of the fermenter and the high reliability of the operation are prominent features of the fermentation industry.

In addition, the washing of fermenters is different from other industrial equipment and is indispensable. The cleaning of the fermenter is of great significance for the protection of product quality. With the continuous advancement of technology, the fermenter will gradually develop towards automation, and the demand for production and cleaning will be in place.

The powerful function makes the fermenter mainly used in three fields, namely food industry, pharmaceutical industry and environmental science. In the food industry, fermenters are commonly used in three major categories of goods: one is to produce traditional fermented goods, such as beer, fruit wine, vinegar, etc.; the second is to produce food additives; the third is to help solve food problems.

In the pharmaceutical industry, according to the skills of fermentation engineering, the development of a variety of drugs, such as human growth hormone, recombinant hepatitis B vaccine, monoclonal antibodies of certain varieties, interleukin-2, anti-hemophilia factor. In environmental science, fermenters are mainly used for microbial enhancement in wastewater treatment. It is understood that the rise of microbial fermentation has driven the increase in demand for fermenters to a certain extent. In the advancement of technology, the effect of fermenters is also constantly changing, which not only improves the safety of fermenters, but also gradually deepens them. People go in their daily lives.

Clearly check the tank process to ensure efficient and error-free production

Regular inspection is a must for any type of equipment, so it is important to understand the inspection process. Regular tank checking of the fermenter helps the user to keep abreast of the state of the fermenter, thereby avoiding production variations due to equipment. So, how to improve the efficiency of the tank inspection tank to ensure efficient production? Jiangsu Fluud Fluid Equipment Co., Ltd. (hereinafter referred to as “Fluud”), which focuses on fermenter manufacturing and technology research and development, shared with the industry. The following experience.

In the air system problem, when the air filter is disinfected and the air is opened, the air opening speed is slow, and the filter element is prevented from being deformed and damaged when the rapid pressure difference changes. In addition, the air filter should be periodically disassembled. When installing a new filter element or disassembling the filter element, carefully check whether the filter element liner is broken or not, and whether the filter O-ring is tight. Also check the moisture content of the compressed air frequently and keep the drain valve at the bottom of the filter unobstructed for a slight venting.

In terms of exhaust pollution, there are three main situations. * The situation is large exhaust. The user needs to check whether the large exhaust system and ventilation are smooth; the second case is sewage. Most of the pipelines on the tank of the fermenter are darkly vented. Therefore, it is necessary to check whether the discharge is unobstructed. When the pressure gauge is observed, the finger touch is also touched. In the third case, the exhaust is exhausted. The fermenter that is exhausted and exhausted should not be heated and insulated at the same time. It is necessary to prevent the pressure from alternating to the exhaust. In addition, it is necessary to regularly check whether the exhaust fan is operating normally. If the fan fails or the suction is insufficient, the disinfection will easily cause the exhaust gas to ruminate into other normal culture fermenters, resulting in bacterial infection.

After the zui, in the daily control, the fermenter needs to be inspected according to the above steps of checking the tank after venting. In addition, it is necessary to regularly use 1-2% alkaline water boiling tank for the fermenter, and if necessary, 1-2% citric acid can be used for boiling the tank. In addition, for frequently used fermenters, the filter should be dismantled every 3 months and disinfected once. The mixing should be dismantled every 6 months, and the seed tanks should be dismantled once every 3 months.

A high-quality fermenter should have good gas, liquid, solid contact and mixing properties, with efficient heat, mass, momentum transfer performance; can reduce the energy consumption of the fermenter under the premise of maintaining biological reaction requirements. In addition, the fermenter must have good heat exchange properties to maintain the temperature of the biological reaction. By doing this, the operator can form a relatively complete and clear tank check process in the future work, thereby improving the efficiency of the tank inspection and ensuring efficient and error-free production.

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