The world's first! Completely paralyzed patients with lower limbs
September 26, 2018 Source: Science and Technology Daily Author: Zhang Meng Ran
Window._bd_share_config={ "common":{ "bdSnsKey":{ },"bdText":"","bdMini":"2","bdMiniList":false,"bdPic":"","bdStyle":" 0","bdSize":"16"},"share":{ }};with(document)0[(getElementsByTagName('head')[0]||body).appendChild(createElement('script')) .src='http://bdimg.share.baidu.com/static/api/js/share.js?v=89860593.js?cdnversion='+~(-new Date()/36e5)];British "Nature·Medical Medicine" published a heavy research on the 25th online: a team of American scientists reported that a patient with complete paralysis of the lower extremities can take another step after receiving spinal cord electrical stimulation and rehabilitation therapy. It is the first in the world.
Severe spinal cord injury can lead to disruption of functional connectivity in the advanced center, causing chronic paralysis. The high-level center is responsible for guiding the movement of the spinal cord circuit under the injury, and the spinal cord circuit interacts directly with the skeletal muscle. The treatment and rehabilitation of spinal cord injury has become a major topic in the medical field. It has been shown that spinal cord electrical stimulation has therapeutic potential, which can promote muscle autonomic contraction and even cause the patient to stand up.
This time, Mayo Clinic scientists Christine Zhao and Kendall Lee reported the first case of human patients who had completely paralyzed their lower extremities after spinal cord injury. The research team conducted a 43-week experiment in which subjects were implanted with spinal cord electrical stimulation devices and received task-specific multimodal rehabilitation training in the research environment.
At the end of the experiment, the patient's leg muscles can produce voluntary contractions that not only support their standing but also step. With the front wheel walker, the patient can walk on the treadmill with the legs, but the stimulator needs to be activated to survive.
This is the first example of a successful reactivation of the long-sleeping human spinal circuit and enabling them to support exercise, but the patient still needs the help of a trainer to maintain balance while using a walker to step on the ground.
The research team concluded that further research is needed at this stage to investigate how rehabilitation training interacts with electrical stimulation to restore the motor function lost by the patient and to verify whether the method can be successfully used for injury type or duration of injury. Different patients.
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