Release date: 2015-06-30
Researchers working on poppy plants have discovered a fusion gene called STORR that facilitates the important, immediate steps in the morphine-producing pathway of the plant; opium poppy is an analgesic like morphine and codeine. The natural source of alkaloids. These findings build on the latest research on yeast and fully clarify the metabolic pathways of morphine; this means an important economic value for obtaining morphine in a cheap and safe way without growing poppy in the field. The method of drugs (and other opioids). Prior to this, researchers have been looking for an enzyme that can change a compound of (S)-Annodamine to a variant of (R)-Annodamine. By studying the poppy plant Papaver somniferum, Thilo Winzer and colleagues found that the STORR enzyme catalyzes two steps: converting (S)-Annodamine to an amine called 1,2-dehydroinosine, and This intermediate substrate is then converted to (R)-an alkaloid. According to the researchers, STORR contains a cytochrome P450 module that facilitates the first step of the process with the oxidoreductase module, while the oxidoreductase module facilitates the second step. With full access to the morphine biosynthesis pathway, researchers can explore more effective, microbiological-based methods for producing opioid analgesics; opioid analgesics generate billions of dollars in annual sales.
Source: Bio 360
Portable Ultrasound Scanner,Ultrasound Scanner Machine,Portable Ultrasound Machine,Laptop Ultrasound Machine
Mianyang United Ultrasound Electronics Co., Ltd , https://www.uniultrasonic.com